The immature platelet fraction: creating neonatal reference intervals and using these to categorize neonatal thrombocytopenias

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The immature platelet fraction (IPF) in neonates

Young (immature) platelets containing residual RNA, so-called reticulated thrombocytes, appear in the peripheral blood after the release from bone marrow. It has been shown that the count of the reticulated platelet correlates with the megakaryocyte mass. As of late, the immature platelet fraction (IPF) may be reliably quantified with the fully automated blood analyzer Sysmex XE-2100. IPF may b...

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Immature platelet fraction: establishment of a reference interval and diagnostic measure for thrombocytopenia.

BACKGROUND Immature platelet fraction (IPF, %) is a measure of reticulated platelets (RPs), which represents the state of thrombopoiesis. The IPF is obtained from an automated hematology analyzer as one of the platelet parameters. This study was performed to establish reference intervals of IPF and its cut-off values for the differential diagnosis of thrombocytopenia. METHODS Blood samples fr...

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ژورنال

عنوان ژورنال: Journal of Perinatology

سال: 2017

ISSN: 0743-8346,1476-5543

DOI: 10.1038/jp.2017.48